Document Detail

Cells, cells, and more cells.
MedLine Citation:
PMID:  17472806     Owner:  NLM     Status:  MEDLINE    
A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma. The serum was positive for the anti-CV2 (anti-CRMP-5) antibody. Following treatment with chemoradiation the optic nerve swelling and vitritis resolved. The differential diagnosis of uveal-meningeal diseases is discussed and the pathophysiology and clinical manifestations of paraneoplastic syndromes reviewed.
M Tariq Bhatti; Katherine E Gres; Virginia B Petitto; Shelley Ann Cross
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Survey of ophthalmology     Volume:  52     ISSN:  0039-6257     ISO Abbreviation:  Surv Ophthalmol     Publication Date:    2007 May-Jun
Date Detail:
Created Date:  2007-05-02     Completed Date:  2007-06-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404551     Medline TA:  Surv Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  315-24     Citation Subset:  IM    
Department of Ophthalmology, Duke University Eye Center and Duke University Medical Center, Durham, North Carolina 27710, USA.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Carcinoma, Small Cell / pathology*,  radiography,  therapy
Combined Modality Therapy
Eye Diseases / pathology*,  radiography,  therapy
Lung Neoplasms
Magnetic Resonance Imaging
Middle Aged
Nerve Tissue Proteins / blood
Papilledema / pathology*,  radiography,  therapy
Paraneoplastic Syndromes / pathology*,  radiography,  therapy
Radiography, Thoracic
Radiotherapy, Conformal
Tomography, X-Ray Computed
Vitreous Body / pathology*
Reg. No./Substance:
0/DPYSL5 protein, human; 0/Nerve Tissue Proteins

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