Document Detail

Cell volume changes during rapid temperature shifts.
MedLine Citation:
PMID:  12795302     Owner:  NLM     Status:  MEDLINE    
The effect of a rapid temperature increase on the volume of different types of cells was investigated. Experiments were carried out using continuous microscopic image analysis. Volume variation of yeast cells, yeast spheroplasts and human leukaemia cells was measured during the transient phase after a thermal shift. The thermal shift was found to induce rapid increase in cell volume for cells lacking a cell wall (yeast spheroplasts and human leukaemia cells). This increase in cell volume is assumed to be a main cause of the heat shock-induced cell death. A theoretical mechanistic model that explains the behaviour of these cells is finally proposed.
Patrick Gervais; Iñigo Martínez de Marañon; Christine Evrard; Eric Ferret; Sylvie Moundanga
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of biotechnology     Volume:  102     ISSN:  0168-1656     ISO Abbreviation:  J. Biotechnol.     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-06-09     Completed Date:  2004-02-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8411927     Medline TA:  J Biotechnol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  269-79     Citation Subset:  IM    
Laboratoire de Génie des Procédés Alimentaires et Biotechnologiques, ENSBANA, 21000 Dijon, France.
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MeSH Terms
Cell Size / radiation effects
Cell Survival / radiation effects
Dose-Response Relationship, Radiation
Heat-Shock Response / physiology*,  radiation effects
Hot Temperature
K562 Cells
Mechanotransduction, Cellular
Models, Biological*
Reproducibility of Results
Saccharomyces cerevisiae / cytology*,  radiation effects
Spheroplasts / cytology*,  radiation effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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