Document Detail


Cell therapy for ischaemic stroke.
MedLine Citation:
PMID:  21481036     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
While acute neuroprotection in acute stroke has proven difficult and ended in many failures, there is increasing interest in restorative therapies that target brain remodelling. Cell therapy (transplantation of cells) shows promise, with a growing body of pre-clinical evidence demonstrating improved functional outcomes in animal models; however, questions still remain concerning mechanisms of action. Clinical trials are already underway and will increase in the next few years; their appropriate design and execution along with continued pre-clinical work are necessary for the field to advance and satisfy a large unmet clinical need.
Authors:
D C Hess; W D Hill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell proliferation     Volume:  44 Suppl 1     ISSN:  1365-2184     ISO Abbreviation:  Cell Prolif.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105195     Medline TA:  Cell Prolif     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
Copyright Information:
© 2011 Blackwell Publishing Ltd.
Affiliation:
Department of Neurology and Cell Biology and Anatomy, Medical College of Georgia, Augusta, 30912, USA. dhess@mcg.edu
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