Document Detail


Cell therapy in children with Down syndrome: a retrospective study.
MedLine Citation:
PMID:  2136948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cell therapy, the administration of freeze-dried or lyophilized cells derived from fetal tissue of animals, has been suggested and accepted by some parents as a treatment for Down syndrome. Such therapy regimens have been purported to ameliorate dysmorphic features and to result in improvement in IQ, motor skills, social behavior, height, language, and memory. Interest in this therapy continues despite a lack of empirical support for its use and its illegality in the United States. In this study, 190 subjects of whom 21 had received cell therapy (from sources external to this study) were studied for 18 variables in the areas of growth, motor development, cognitive development, and adaptive/social status. Comparing the cell-treated group with a control group matched for sex, age, socioeconomic status, and cardiac history showed no statistically significant differences for any of the developmental or growth variables measured. These findings fail to support continued claims of improved functioning following cell therapy in persons with Down syndrome.
Authors:
D C Van Dyke; D J Lang; S van Duyne; F Heide; H J Chang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  85     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-02-14     Completed Date:  1990-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  79-84     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City 52242.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Cattle
Child
Child, Preschool
Cognition
Complementary Therapies
Down Syndrome / pathology,  psychology,  therapy*
Female
Freeze Drying
Growth
Humans
Infant
Intelligence
Male
Psychomotor Performance
Rabbits
Retrospective Studies
Sheep
Social Behavior
Tissue Therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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