Document Detail


Cell surface engineering of microorganisms towards adsorption of heavy metals.
MedLine Citation:
PMID:  23915280     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Heavy metal contamination has become a worldwide environmental concern due to its toxicity, non-degradability and food-chain bioaccumulation. Conventional physical and chemical treatment methods for heavy metal removal have disadvantages such as cost-intensiveness, incomplete removal, secondary pollution and the lack of metal specificity. Microbial biomass-based biosorption is one of the approaches gaining increasing attention because it is effective, cheap, and environmental friendly and can work well at low concentrations. To enhance the adsorption properties of microbial cells to heavy metal ions, the cell surface display of various metal-binding proteins/peptides have been performed using a cell surface engineering approach. The surface engineering of Gram-negative bacteria, Gram-positive bacteria and yeast towards the adsorption of heavy metals are reviewed in this article. The problems and future perspectives of this technology are discussed.
Authors:
Peng-Song Li; Hu-Chun Tao
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-8-5
Journal Detail:
Title:  Critical reviews in microbiology     Volume:  -     ISSN:  1549-7828     ISO Abbreviation:  Crit. Rev. Microbiol.     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-8-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8914274     Medline TA:  Crit Rev Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Peking University Shenzhen Graduate School, School of Environment and Energy, Key Laboratory for Heavy Metal Pollution Control and Reutilization , Shenzhen , China.
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