Document Detail

Cell size following irradiation in relation to cell cycle.
MedLine Citation:
PMID:  3030055     Owner:  NLM     Status:  MEDLINE    
The cell volume of Ehrlich ascites tumour cells was studied following a radiation dose of 5.0 Gy. The cell volume increased 12 to 30 hours after irradiation by about 20 per cent, was normal at about 50 hours, and increased again at 72 hours. In order to explain these changes the composition of the cells in cell cycle was studied. In addition, the cell volume of irradiated cells from the various parts of the cell cycle, separated by centrifugal elutriation, was measured. The changes in the mean cell volume of unseparated cells could be explained by variations in the cell cycle composition of the cell population. Irradiated cells from the various parts of the cell cycle did not deviate from the volume of non-irradiated cells. The cell volume doubled during the cell cycle. This increase was, however, not linear.
S Skog; B Tribukait
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta radiologica. Oncology     Volume:  25     ISSN:  0349-652X     ISO Abbreviation:  Acta Radiol Oncol     Publication Date:    1986 Jul-Dec
Date Detail:
Created Date:  1987-04-16     Completed Date:  1987-04-16     Revised Date:  2006-12-05    
Medline Journal Info:
Nlm Unique ID:  8209606     Medline TA:  Acta Radiol Oncol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  269-73     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Ehrlich Tumor / pathology
Cell Count
Cell Cycle*
Cell Survival / radiation effects*
DNA, Neoplasm / analysis
Mice, Inbred Strains
Reg. No./Substance:
0/DNA, Neoplasm

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