| Cell proliferation in a malignant angioendothelioma during sequential chemotherapy. | |
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MedLine Citation:
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PMID: 521539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rate of cellular proliferation was studied in the neoplastic cells of a malignant angioendothelioma and in its inflammatory infiltrate by means of optical radioautography after incorporation ex vivo of tritiated thymidine. One third of the normal looking, as well as the atypical, endothelial cells were engaged in the cell cycle of proliferation. This large pool has been effectively suppressed during subsequent chemotherapy which resulted in partial regression of the neoplasm. The proliferative activity of the infiltrate was higher inside the neoplasm than at its periphery. |
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Authors:
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G E Pierard; C Focan; C M Lapiere |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of cutaneous pathology Volume: 6 ISSN: 0303-6987 ISO Abbreviation: J. Cutan. Pathol. Publication Date: 1979 Dec |
Date Detail:
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Created Date: 1980-03-27 Completed Date: 1980-03-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0425124 Medline TA: J Cutan Pathol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 479-85 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Autoradiography Cell Transformation, Neoplastic / pathology* Cyclophosphamide / therapeutic use Doxorubicin / therapeutic use Drug Therapy, Combination Hemangioendothelioma / drug therapy, pathology* Humans Male Methotrexate / therapeutic use Scalp / pathology Skin Neoplasms / drug therapy, pathology* Vinblastine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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23214-92-8/Doxorubicin; 50-18-0/Cyclophosphamide; 59-05-2/Methotrexate; 865-21-4/Vinblastine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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