Document Detail


Cell proliferation in follicle-associated epithelium of mouse Peyer's patch.
MedLine Citation:
PMID:  7446446     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Follicle-associated epithelium (FAE) from the mouse Peyer's patch consists of a dome part containing goblet as well as columnar epithelial cells and a crypt part, containing Paneth as well as goblet and undifferentiated epithelial cells. The proportions of columnar epithelial, goblet and Paneth cells in the FAE are similar to those found in normal crypt/villus complexes. Mitosis is confined to the crypts of the FAE. The cell-renewal time for FAE columnar epithelial cells, estimated from experiments using tritiated thymidine, is approximately 60 hours. Large numbers of lymphoid cells are also present in the FAE, particularly in regions distal to the crypts. The similarity between follicle-associated and villus epithelial structure is discussed, together with its possible relevance to "M" cell formation within the FAE.
Authors:
M W Smith; L G Jarvis; I S King
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of anatomy     Volume:  159     ISSN:  0002-9106     ISO Abbreviation:  Am. J. Anat.     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-02-26     Completed Date:  1981-02-26     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376312     Medline TA:  Am J Anat     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  157-66     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Epithelial Cells
Kinetics
Lymphocytes / cytology
Lymphoid Tissue / cytology*
Male
Mice
Mice, Inbred A
Mitosis
Peyer's Patches / cytology*
Thymidine / metabolism
Chemical
Reg. No./Substance:
50-89-5/Thymidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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