Document Detail

Cell polarity: tension quenches the rear.
MedLine Citation:
PMID:  22280905     Owner:  NLM     Status:  In-Data-Review    
A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.
Alex Mogilner; Jie Zhu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current biology : CB     Volume:  22     ISSN:  1879-0445     ISO Abbreviation:  Curr. Biol.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  R48-51     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Department of Neurobiology, Physiology and Behavior and Department of Mathematics, University of California, Davis, CA 95616, USA.
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