Document Detail


Cell-mediated immunity to respiratory virus infections.
MedLine Citation:
PMID:  12900275     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The mucosal surfaces of the lungs pose tremendous problems for an immune system charged with maintaining a sterile pulmonary environment. Despite these problems, the immune system is effective at controlling most pulmonary infections. Over the past few years significant progress has been made in our understanding of how adaptive (humoral and cellular) immunity is able to control infections in the respiratory tract. Recent advances include the identification of effector memory T-cell populations in the lungs and an appreciation for the role of cytokines in regulating memory T-cell pools.
Authors:
David L Woodland
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in immunology     Volume:  15     ISSN:  0952-7915     ISO Abbreviation:  Curr. Opin. Immunol.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-08-05     Completed Date:  2004-03-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  430-5     Citation Subset:  IM    
Affiliation:
Trudeau Institute, New York, NY 12983, USA. dwoodland@trudeauinstitute.org
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MeSH Terms
Descriptor/Qualifier:
Humans
Immunologic Memory / immunology
Respiratory Tract Infections / immunology*,  virology*
T-Lymphocytes / immunology*
Vaccination
Virus Diseases / immunology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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