Document Detail

Cell-mediated immune reactivity to ocular antigens in rheumatoid arthritis.
MedLine Citation:
PMID:  6762043     Owner:  NLM     Status:  MEDLINE    
Fourteen patients with rheumatoid arthritis were tested for the presence of cell-mediated immune reactivity to various ocular antigens by means of the leucocyte migration inhibition test. A significant difference in leucocyte migration was found between patients and healthy controls after incubation of their cells with purified rhodopsin, uveal pigment granules or soluble uveal antigens, but not with rod outer segments or soluble retinal antigens. Some indications have been obtained that the sensitization to rhodopsin in fact originates from a sensitization to connective tissue structural glycoproteins.
R M Broekhuyse; L B van de Putte; A J Pinckers; C J Brinkman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  60     ISSN:  0001-639X     ISO Abbreviation:  Acta Ophthalmol (Copenh)     Publication Date:  1982 Oct 
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370347     Medline TA:  Acta Ophthalmol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  815-20     Citation Subset:  IM    
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MeSH Terms
Antigens / immunology*
Arthritis, Rheumatoid / immunology*
Connective Tissue / immunology
Eye / immunology*
Glycoproteins / immunology
Immunity, Cellular*
Leukocyte Migration-Inhibitory Factors / analysis
Middle Aged
Retinal Pigments / immunology
Rhodopsin / immunology
Reg. No./Substance:
0/Antigens; 0/Glycoproteins; 0/Leukocyte Migration-Inhibitory Factors; 0/Retinal Pigments; 9009-81-8/Rhodopsin

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