Document Detail

Cell killing by avian leukosis viruses.
MedLine Citation:
PMID:  6270346     Owner:  NLM     Status:  MEDLINE    
Infection of chicken cells with a cytopathic avian leukosis virus resulted in the detachment of killed cells from the culture dish. The detached, dead cells contained more unintegrated viral DNA than the attached cells. These results confirm the hypothesis that cell killing after infection with a cytopathic avian leukosis virus is associated with accumulation of large amounts of unintegrated viral DNA. No accumulation of large amounts of integrated viral DNA was found in cells infected with cytopathic avian leukosis viruses.
S K Weller; H M Temin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of virology     Volume:  39     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1981 Sep 
Date Detail:
Created Date:  1981-12-22     Completed Date:  1981-12-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  713-21     Citation Subset:  IM    
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MeSH Terms
Avian leukosis virus / genetics,  physiology*
Cell Adhesion
Cell Survival*
Cells, Cultured
Chick Embryo
Cytopathogenic Effect, Viral*
DNA / metabolism
DNA, Viral / metabolism*
Recombination, Genetic
Grant Support
Reg. No./Substance:
0/DNA, Viral; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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