| Cell interactions in the sea urchin embryo studied by fluorescence photoablation. | |
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MedLine Citation:
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PMID: 2188366 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In many organisms, interactions between cells play a critical role in the specification of cell fates. In the sea urchin embryo, primary mesenchyme cells (PMCs) regulate the developmental program of a subpopulation of secondary mesenchyme cells (SMCs). The timing of this cell interaction was analyzed by means of a fluorescence photoablation technique, which was used to specifically ablate PMCs at various stages of development. In addition, the PMCs were microinjected into PMC-depleted recipient embryos at different developmental stages and their effect on SMC fate was examined. The critical interaction between PMCs and SMCs was brief and took place late in gastrulation. Before that time, SMCs were insensitive to the suppressive signals transmitted by the PMCs. |
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Authors:
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C A Ettensohn |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 248 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1990-06-26 Completed Date: 1990-06-26 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1115-8 Citation Subset: IM |
Affiliation:
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Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Communication / physiology* Cell Survival / radiation effects Fluorescent Antibody Technique Fluorescent Dyes / diagnostic use Light Mesoderm / cytology*, radiation effects Microinjections Rhodamines / diagnostic use Sea Urchins / embryology |
| Grant Support | |
ID/Acronym/Agency:
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HD24690/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fluorescent Dyes; 0/Rhodamines; 36877-69-7/rhodamine isothiocyanate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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