Document Detail

Cell growth and shikonin production of Arnebia euchroma in a periodically submerged airlift bioreactor.
MedLine Citation:
PMID:  16614888     Owner:  NLM     Status:  MEDLINE    
Arnebia euchroma was grown in a 2-l periodically submerged, airlift bioreactor (PSAB) in which the non-submerged (immobilization culture) and submerged (suspension culture) operations were controlled automatically. PSAB had advantages in improving cell growth, shikonin content, shikonin production and cell aggregation compared with suspension culture. Under the optimal submerged/non-submerged period of 10 min/15 h, the shikonin content (4.6%, w/w) and, cell dry mass (16.8 g/l) were 229 and 26% higher than those in suspension culture.
Feng Ge; Xiaofan Yuan; Xiaodong Wang; Bing Zhao; Yuchun Wang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biotechnology letters     Volume:  28     ISSN:  0141-5492     ISO Abbreviation:  Biotechnol. Lett.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-14     Completed Date:  2006-11-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008051     Medline TA:  Biotechnol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  525-9     Citation Subset:  IM    
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P. O. Box 353, Beijing 100080, China.
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MeSH Terms
Boraginaceae / cytology,  growth & development*,  metabolism*
Cell Division
Culture Techniques / instrumentation,  methods
Naphthoquinones / metabolism*
Time Factors
Reg. No./Substance:
0/Naphthoquinones; 54952-43-1/shikonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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