Document Detail

Cell-free passive transfer of delayed hypersensitivity to chemicals in guinea pigs.
MedLine Citation:
PMID:  5154895     Owner:  NLM     Status:  MEDLINE    
Delayed-type cutaneous reactivity to 2,4-dinitrochlorobenzene and 2,4-dinitrofluorobenzene in guinea pigs was transferred passively by fluids in which leukocytes from sensitive animals were incubated. Cells from peritoneal exudates, lymph nodes, and alveolar washings were employed. The cell-free transfer material was dialyzable, of small molecular size, and stable to 56 C for 30 min and -65 C for at least 9 weeks. It gave a ratio at 280 to 260 nm of 0.71. The relationships between temperature, pH, and cellular release of the transfer material were studied.
D R Burger; W S Jeter
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Infection and immunity     Volume:  4     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1971 Nov 
Date Detail:
Created Date:  1973-01-05     Completed Date:  1973-01-05     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  575-80     Citation Subset:  IM    
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MeSH Terms
Antibodies / analysis
Cell-Free System
Chlorine / adverse effects
Cross Reactions
Exudates and Transudates
Fluorine / adverse effects
Guinea Pigs
Hydrogen-Ion Concentration
Hypersensitivity, Delayed / chemically induced*
Immunization, Passive*
Leukocyte Count
Leukocytes / drug effects
Lymph Nodes / immunology
Nitrobenzenes / adverse effects*
Peritoneum / immunology
Precipitin Tests
Skin Tests
Spectrum Analysis
Reg. No./Substance:
0/Antibodies; 0/Nitrobenzenes; 7782-41-4/Fluorine; 7782-50-5/Chlorine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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