| Cell-free nucleic acids as biomarkers in cancer patients. | |
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MedLine Citation:
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PMID: 21562580 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic acids have been associated with tumour burden and malignant progression. In the past decade a wealth of information indicating the potential use of circulating nucleic acids for cancer screening, prognosis and monitoring of the efficacy of anticancer therapies has emerged. In this Review, we discuss these findings with a specific focus on the clinical utility of cell-free nucleic acids as blood biomarkers. |
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Authors:
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Heidi Schwarzenbach; Dave S B Hoon; Klaus Pantel |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-12 |
Journal Detail:
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Title: Nature reviews. Cancer Volume: - ISSN: 1474-1768 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101124168 Medline TA: Nat Rev Cancer Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institute of Tumour Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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