| Cell-free biology: Exploiting the interface between synthetic biology and synthetic chemistry. | |
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MedLine Citation:
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PMID: 22483202 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Just as synthetic organic chemistry once revolutionized the ability of chemists to build molecules (including those that did not exist in nature) following a basic set of design rules, cell-free synthetic biology is beginning to provide an improved toolbox and faster process for not only harnessing but also expanding the chemistry of life. At the interface between chemistry and biology, research in cell-free synthetic systems is proceeding in two different directions: using synthetic biology for synthetic chemistry and using synthetic chemistry to reprogram or mimic biology. In the coming years, the impact of advances inspired by these approaches will make possible the synthesis of nonbiological polymers having new backbone compositions, new chemical properties, new structures, and new functions. |
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Authors:
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D Calvin Harris; Michael C Jewett |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-4 |
Journal Detail:
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Title: Current opinion in biotechnology Volume: - ISSN: 1879-0429 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9100492 Medline TA: Curr Opin Biotechnol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA; Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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