Document Detail


Cell division and the nervous system: regulating the cycle from neural differentiation to death.
MedLine Citation:
PMID:  8820869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It has long been recognized that the balance between cellular proliferation and cell death during embryogenesis is a key factor in formation of the CNS. The recent definition of molecular mechanisms that drive the cell-division cycle and programmed cell death provides an opportunity to investigate the molecular interactions that co-ordinate cell-cycle regulation with CNS-pattern formation, neural differentiation and histogenesis. It is proposed that not only is the cell-division cycle regulated by developmentally controlled molecular signals to halt or proceed, but gene products that drive the cycle can also influence the course of neural differentiation and apoptosis.
Authors:
M E Ross
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Trends in neurosciences     Volume:  19     ISSN:  0166-2236     ISO Abbreviation:  Trends Neurosci.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-10-30     Completed Date:  1996-10-30     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7808616     Medline TA:  Trends Neurosci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  62-8     Citation Subset:  IM    
Affiliation:
Dept of Neurology, University of Minnesota, Minneapolis 55455, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Apoptosis / physiology
Cell Cycle / physiology*
Cell Death / physiology
Cell Differentiation / physiology
Cell Division / physiology
Humans
Nervous System / cytology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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