Document Detail


Cell death: shadow baxing.
MedLine Citation:
PMID:  9705928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bcl-2, one of a family of key regulators of apoptosis, was the first cell-death machinery component to be identified, but how the family functions is still not clear. Mammalian Bax, a pro-apoptotic family member, can cause yeast cells to die, and two recent yeast genetic screens shed light on how Bax might function.
Authors:
J Silke; D L Vaux
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current biology : CB     Volume:  8     ISSN:  0960-9822     ISO Abbreviation:  Curr. Biol.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-11-20     Completed Date:  1998-11-20     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  R528-31     Citation Subset:  IM    
Affiliation:
Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia. silke@wehi.edu.au
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Animals
Apoptosis / physiology*
Molecular Sequence Data
Proto-Oncogene Proteins / physiology*
Proto-Oncogene Proteins c-bcl-2 / physiology*
bcl-2-Associated X Protein
Chemical
Reg. No./Substance:
0/Proto-Oncogene Proteins; 0/Proto-Oncogene Proteins c-bcl-2; 0/bcl-2-Associated X Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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