| Cell death during early morphogenesis: parallels between insect limb and vertebrate limb development. | |
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MedLine Citation:
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PMID: 5773109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The complex jointed leg of the adult fly is derived, in the pupal stage, from a simple lobed sac of cells. The gross morphological changes that result in adult shape are effected by a combination of differential cell growth and the programmed death of a large number of imaginal disc cells. Events are closely similar to those occurring in digit formation and limb contouring during vertebrate morphogenesis. In both cases phagocytic blood cells are intimately involved. |
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Authors:
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J M Whitten |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 163 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1969 Mar |
Date Detail:
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Created Date: 1969-04-22 Completed Date: 1969-04-22 Revised Date: 2011-12-07 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1456-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Clocks Diptera / growth & development* Extremities / growth & development* Genetics Morphogenesis Necrosis Phagocytosis Physiology, Comparative Vertebrates |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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