| Cell damage in vitro following direct contact with fine particles of titanium, titanium alloy and cobalt-chrome-molybdenum alloy. | |
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MedLine Citation:
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PMID: 7948594 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fibroblastic cells in vitro were exposed to powders of titanium, titanium-aluminium-vanadium alloy and cobalt-chrome-molybdenum (Co-Cr-Mo) alloy, either in direct contact with the cells or separated from the cells by a microporous membrane. Fine particles of all the materials reduced cell growth when in direct contact with cells, but only the finest particles of Co-Cr-Mo alloy caused cell damage through the microporous membrane. This provides further evidence that there is a mechanism of cell damage in vitro which depends on a direct interaction between cells and particles and is largely independent of the chemical nature of the particle. |
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Authors:
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E J Evans |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biomaterials Volume: 15 ISSN: 0142-9612 ISO Abbreviation: Biomaterials Publication Date: 1994 Jul |
Date Detail:
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Created Date: 1994-12-28 Completed Date: 1994-12-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8100316 Medline TA: Biomaterials Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 713-7 Citation Subset: IM |
Affiliation:
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Department of Anatomy, University of Wales College of Cardiff, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Count / drug effects Cells, Cultured Fibroblasts / cytology, drug effects* Particle Size Rats Titanium / toxicity* Vitallium / toxicity* |
| Chemical | |
Reg. No./Substance:
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12629-02-6/Vitallium; 12743-70-3/titanium alloy (TiAl6V4); 7440-32-6/Titanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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