Document Detail

Cell cycle dependent exposure of a high molecular weight protein on the surface of mouse L cells.
MedLine Citation:
PMID:  1238124     Owner:  NLM     Status:  MEDLINE    
The non-penetrating lactoperoxidase iodination probe has been employed in conjunction with synchronously dividing populations of mouse L cells to identify a high molecular weight protein is preferentially exposed on the L cell surface during G1 phase of the cell cycle. Progression of cells from G1 to S is accompanied by a marked decrease in tha availability of this structure, called band 1, to lactoperoxidase-catalyzed iodination and it remains unavailable until cells re-enter G1. It is suggested that the band 1 polypeptide may be functionally involved in the regulation of L cell growth.
R C Hunt; E Gold; J C Brown
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biochimica et biophysica acta     Volume:  413     ISSN:  0006-3002     ISO Abbreviation:  Biochim. Biophys. Acta     Publication Date:  1975 Dec 
Date Detail:
Created Date:  1976-02-26     Completed Date:  1976-02-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0217513     Medline TA:  Biochim Biophys Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  453-8     Citation Subset:  IM    
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MeSH Terms
Cell Division
Cell Membrane / metabolism*,  ultrastructure
L Cells (Cell Line) / metabolism*
Molecular Weight
Proteins / metabolism*
Thymidine / metabolism
Time Factors
Reg. No./Substance:
0/Proteins; 50-89-5/Thymidine; EC 1.11.1.-/Lactoperoxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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