| Cell cycle control of morphogenesis in budding yeast. | |
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MedLine Citation:
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PMID: 7749320 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A detailed description of the cytoskeletal rearrangements that orchestrate bud formation is beginning to emerge from studies on yeast morphogenesis. In this review, we focus on recent advances in our understanding of how the timing of these rearrangements is controlled. Dramatic changes in cell polarity that occur in G1 (polarization to the bud site), G2 (depolarization within the bud), and mitosis (repolarization to the mother/bud neck) are triggered by changes in the kinase activity of Cdc28, the universal regulator of cell cycle progression. The hunt for Cdc28 morphogenesis substrates is on. |
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Authors:
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D J Lew; S I Reed |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Current opinion in genetics & development Volume: 5 ISSN: 0959-437X ISO Abbreviation: Curr. Opin. Genet. Dev. Publication Date: 1995 Feb |
Date Detail:
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Created Date: 1995-06-20 Completed Date: 1995-06-20 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 9111375 Medline TA: Curr Opin Genet Dev Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 17-23 Citation Subset: IM |
Affiliation:
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Duke University Medical Center, Durham, North Carolina 27710, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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CDC28 Protein Kinase, S cerevisiae
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physiology Cell Cycle / physiology* Cyclins / physiology Cytoskeleton / metabolism Morphogenesis Saccharomyces cerevisiae / cytology* |
| Grant Support | |
ID/Acronym/Agency:
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GM38328/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Cyclins; EC 2.7.11.22/CDC28 Protein Kinase, S cerevisiae |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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