| Cell cycle control during the contact mediated growth inhibition of rat C6 glioma cells. | |
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MedLine Citation:
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PMID: 3802215 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two separate control processes govern the cell cycle of rat C6 glioma cells. In subconfluent cultures growth inhibition is caused by cell contact interactions and the cell cycle is regulated primarily by changes in the duration of S phase. During advanced multilayering, medium depletion becomes the primary mechanism of growth inhibition and causes a pronounced G1 accumulation. Contact modulation acts by altering the velocity with which cells progress through the cell cycle, while depletion causes cycle arrest. |
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Authors:
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P Skehan; J E Thomas; S J Friedman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cell biology international reports Volume: 10 ISSN: 0309-1651 ISO Abbreviation: Cell Biol. Int. Rep. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-03-10 Completed Date: 1987-03-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7708050 Medline TA: Cell Biol Int Rep Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 939-46 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Communication* Cell Cycle* Cell Division Cell Line Glioma / pathology* Interphase Rats |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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