Document Detail

Cell culture as a tool for the study of poultry skeletal muscle development.
MedLine Citation:
PMID:  1371806     Owner:  NLM     Status:  MEDLINE    
Postnatal development of skeletal muscle is the responsibility of the myogenic satellite cells. Satellite cells, isolated from the pectoralis major muscle of young growing tom turkeys, have been cultured in vitro to provide a system for studying cellular and hormonal aspects of poultry skeletal muscle development. Satellite cell clones derived from primary cultures have been developed so that in vitro observations would not be confounded by the presence of nonmyogenic cells. Likewise, a serum-free medium that promotes proliferation of the turkey satellite cell has been developed to provide a hormonally controlled environment for in vitro developmental studies. These two techniques have enabled us to examine the following: 1) factors that influence satellite cell proliferation and differentiation, 2) the interaction of hormones with cellular receptors, 3) secretion of biologically important proteins from cells and 4) the expression of genes important to muscle development.
D C McFarland
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  The Journal of nutrition     Volume:  122     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-04-06     Completed Date:  1992-04-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  818-29     Citation Subset:  IM    
Department of Animal and Range Sciences, South Dakota State University, Brookings 57007-0392.
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MeSH Terms
Carrier Proteins / physiology
Cells, Cultured
Chick Embryo
Growth Substances / physiology
Insulin-Like Growth Factor Binding Proteins
Muscle Development*
Poultry / growth & development*
Receptors, Cell Surface / physiology
Receptors, Somatomedin
Reg. No./Substance:
0/Carrier Proteins; 0/Growth Substances; 0/Insulin-Like Growth Factor Binding Proteins; 0/Receptors, Cell Surface; 0/Receptors, Somatomedin

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