Document Detail

Cell-cell organization and functions of 'sinusoids' in liver microcirculation system.
MedLine Citation:
PMID:  10356785     Owner:  NLM     Status:  MEDLINE    
Following much controversy through the first three decades in this century structure and function of hepatic sinusoids have been elucidated. The sinusoidal wall consists of endothelial cells, Kupffer cells, dendritic cells, NK cells (pit cells) and stellate cells. Using classic staining methods, immunocytochemistry, fluorescence microscopy, TEM and SEM, cell-cell organizations and functions of sinusoids have been studied. Based on observations, a new definition of the space of Disse was proposed.
K Wake
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electron microscopy     Volume:  48     ISSN:  0022-0744     ISO Abbreviation:  J Electron Microsc (Tokyo)     Publication Date:  1999  
Date Detail:
Created Date:  1999-07-20     Completed Date:  1999-07-20     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7611157     Medline TA:  J Electron Microsc (Tokyo)     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  89-98     Citation Subset:  IM    
Department of Anatomy, School of Medicine, Tokyo Medical and Dental University, Japan.
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MeSH Terms
Dendritic Cells / chemistry,  ultrastructure
Endothelium, Vascular / chemistry,  cytology
Killer Cells, Natural / chemistry,  ultrastructure
Kupffer Cells / chemistry,  ultrastructure
Liver / blood supply*,  cytology*,  metabolism
Microscopy, Electron
Microscopy, Electron, Scanning
Microscopy, Fluorescence
Staining and Labeling / methods

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