Document Detail

Cell-cell communication in the pituitary: orchestrator of pulsatile growth hormone secretion?
MedLine Citation:
PMID:  16938459     Owner:  NLM     Status:  MEDLINE    
Hormone secretion is dependent on intracellular and extracellular regulation of hormone synthesis and release, including classical endocrine and paracrine mechanisms and transcription factors that determine cell differentiation and hormone gene transcription. Recent research has identified direct cell-cell communication in a three-dimensional network of pituitary growth hormone-secreting cells connected by adherens junctions. This challenges the conventional view of endocrine cells as collections of dispersed cells and suggests that physical connectivity mediates cellular responses to coordinate pulsatile secretion.
Sylvia L Asa; Gloria S Tannenbaum
Related Documents :
8391329 - Heterogeneity in the storage of gonadotropins in the ovine fetus and evidence for lutei...
10831159 - Different effects of melatonin pretreatment on camp and lh responses of the neonatal ra...
12972179 - Laminin inhibits lactotroph proliferation and is reduced in early prolactinoma developm...
20029839 - A proteome map of the pituitary melanotrope cell activated by black-background adaptati...
393399 - Gonadotroph-rich cell lines derived from pituitary clonal cells (2a8) grafted under the...
1468769 - Contribution of immunohistochemistry, electron microscopy, and cell culture to the char...
21111709 - Repair pathways independent of the fanconi anemia nuclear core complex play a predomina...
14990389 - Model of the developing tumorigenic phenotype in mammalian cells and the roles of susta...
20806009 - Atp-induced morphological changes in supporting cells of the developing cochlea.
Publication Detail:
Type:  Journal Article; Review     Date:  2006-08-30
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  17     ISSN:  1043-2760     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-25     Completed Date:  2007-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-300     Citation Subset:  IM    
Department of Laboratory Medicine and Pathobiology, University of Toronto and Department of Pathology, University Health Network and Toronto Medical Laboratories, Toronto, Ontario M5G 2C4, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cell Communication / physiology
Growth Hormone / biosynthesis,  secretion*
Pituitary Gland / physiology,  secretion*
Pulsatile Flow / physiology
Somatotrophs / secretion
Reg. No./Substance:
9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Probing the electronic structure of ZnO nanowires by valence electron energy loss spectroscopy.
Next Document:  Importance of TNFalpha and neutral lipases in human adipose tissue lipolysis.