| Cell cannibalism: diagnostic marker of malignancy. | |
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MedLine Citation:
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PMID: 12561027 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study, we tried to find out the cytological relevance of cannibalism as a dependable feature of malignancy in effusion and urine cytology. We randomly selected a total of 40 cases consisting of 10 each of malignant effusion, benign effusion, malignant urine samples, and benign urine samples. These smears were assessed for the presence of cell cannibalism. The number of cannibalistic cells/100 tumor cells was counted. The cannibalistic cells were seen more commonly in malignant effusion cases (3.4/100 cells) compared with malignant urine cases (2/100 cells). There was not a single cannibalistic cell in benign conditions. The finding of an increased number of cannibalistic cell was highly significant in malignant versus benign samples (P > 0.0000, Student's t-test). The present study highlights the significance of cannibalism in malignant urine and effusion cytology. We suggest that cell cannibalism is a dependable cytological feature of malignancy. |
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Authors:
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Kirti Gupta; Pranab Dey |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Diagnostic cytopathology Volume: 28 ISSN: 8755-1039 ISO Abbreviation: Diagn. Cytopathol. Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-01-31 Completed Date: 2003-08-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8506895 Medline TA: Diagn Cytopathol Country: United States |
Other Details:
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Languages: eng Pagination: 86-7 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
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Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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diagnosis* Carcinoma / diagnosis*, urine Cell Death Cell Nucleus Cell Size Cytodiagnosis / methods Exudates and Transudates / cytology Humans Predictive Value of Tests Tumor Markers, Biological* Urologic Neoplasms / diagnosis* |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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