Document Detail


Cell biology and immunology of Listeria monocytogenes infections: novel insights.
MedLine Citation:
PMID:  21349093     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Summary:  Listeria monocytogenes is an intracellular bacterium responsible for a disease characterized by several clinical features, such as septicemia, brain infection, abortion, and perinatal infection. These clinical features are attributed to its amazing capacity to cross several barriers in susceptible hosts. Intracellular infection is a consequence of the bacterium's capacity to enter a wide variety of mammalian cells, to not only survive but also replicate therein, and to its faculty to spread from one cell to the next, thereby escaping the humoral immune response. Here, we review both the well-established and the newly discovered strategies used by this bacterium to achieve this intracellular lifestyle while escaping from the host innate immune response. More than ever, Listeria appears as a model system and a reference in infection biology.
Authors:
Fabrizia Stavru; Cristel Archambaud; Pascale Cossart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Immunological reviews     Volume:  240     ISSN:  1600-065X     ISO Abbreviation:  Immunol. Rev.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7702118     Medline TA:  Immunol Rev     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  160-84     Citation Subset:  IM    
Copyright Information:
© 2011 John Wiley & Sons A/S.
Affiliation:
Unité des Interactions Bactéries-Cellules, Institut Pasteur, U604 INSERM, USC2020 INRA Paris, France.
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