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Cell-based therapy of diabetes: What are the new sources of beta cells?
MedLine Citation:
PMID:  21778101     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Diabetes affects 246 million people around the world. To date, no definitive cure has been discovered. Recent clinical trials have shed light on the possibility of successfully transplanting adult pancreatic islets into type 1 diabetic recipients. However, despite encouraging efforts to improve such protocols, the poor availability of pancreatic islets remains a limiting parameter for these transplantation programmes. In the present review, different strategies to obtain other sources of islet beta cells are discussed.
Authors:
A Soggia; E Hoarau; C Bechetoille; M-T Simon; M Heinis; B Duvillié
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-19
Journal Detail:
Title:  Diabetes & metabolism     Volume:  -     ISSN:  1878-1780     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607599     Medline TA:  Diabetes Metab     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Masson SAS.
Affiliation:
Inserm U845, Research Center Growth and Signalling, Hôpital Necker, Faculté de Médecine, Université Paris Descartes, 156, rue de Vaugirard, 75015 Paris, France.
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