Document Detail


Cell immobilization for production of lactic acid biofilms do it naturally.
MedLine Citation:
PMID:  20378053     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Interest in natural cell immobilization or biofilms for lactic acid fermentation has developed considerably over the last few decades. Many studies report the benefits associated with biofilms as industrial methods for food production and for wastewater treatment, since the formation represents a protective means of microbial growth offering survival advantages to cells in toxic environments. The formation of biofilms is a natural process in which microbial cells adsorb to a support without chemicals or polymers that entrap the cells and is dependent on the reactor environment, microorganism, and characteristics of the support. These unique characteristics enable biofilms to cause chronic infections, disease, food spoilage, and devastating effects as in microbial corrosion. Their distinct resistance to toxicity, high biomass potential, and improved stability over cells in suspension make biofilms a good tool for improving the industrial economics of biological lactic acid production. Lactic acid bacteria and specific filamentous fungi are the main sources of biological lactic acid. Over the past two decades, studies have focused on improving the lactic acid volumetric productivity through reactor design development, new support materials, and improvements in microbial production strains. To illustrate the operational designs applied to the natural immobilization of lactic acid producing microorganisms, this chapter presents the results of a search for optimum parameters and how they are affected by the physical, chemical, and biological variables of the process. We will place particular emphasis upon the relationship between lactic acid productivity attained by various types of reactors, supports, media formulations, and lactic acid producing microorganisms.
Authors:
Suzanne F Dagher; Alicia L Ragout; Faustino Si?eriz; Jos? M Bruno-B?rcena
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-02-20
Journal Detail:
Title:  Advances in applied microbiology     Volume:  71     ISSN:  0065-2164     ISO Abbreviation:  Adv. Appl. Microbiol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-04-09     Completed Date:  2010-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370413     Medline TA:  Adv Appl Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  113-48     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Microbiology, North Carolina State University, Raleigh, North Carolina, USA.
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MeSH Terms
Descriptor/Qualifier:
Biofilms / growth & development*
Bioreactors
Biotechnology / methods
Cells, Immobilized*
Fermentation
Industrial Microbiology / methods*
Lactic Acid / biosynthesis*
Lactobacillus / classification,  growth & development,  metabolism,  physiology*
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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