Document Detail


Celiac disease: an underappreciated issue in women’s health.
MedLine Citation:
PMID:  20887172     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Celiac disease (CD) is an immune-mediated enteropathy that is secondary to gluten ingestion and classically associated with gastrointestinal symptoms. Diagnosis is based on serology and confirmatory duodenal biopsy, and the only treatment is lifelong avoidance of gluten. CD has been increasingly recognized to encompass a wide variety of manifestations that are relevant to women’s health, including infertility, adverse pregnancy outcomes and reduced BMD. Currently, CD is underdiagnosed, largely owing to lack of recognition of the diverse manifestations by general practitioners. Increased awareness of the clinical spectrum of this disease, as well as targeted testing in at-risk individuals (including women with unexplained infertility and previous adverse pregnancy outcomes, and in specific populations with reduced BMD) is greatly needed in order to improve rates of diagnosis.
Authors:
Sveta Shah; Daniel Leffler
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Women's health (London, England)     Volume:  6     ISSN:  1745-5065     ISO Abbreviation:  Womens Health (Lond Engl)     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-04     Completed Date:  2011-01-18     Revised Date:  2013-08-29    
Medline Journal Info:
Nlm Unique ID:  101271249     Medline TA:  Womens Health (Lond Engl)     Country:  England    
Other Details:
Languages:  eng     Pagination:  753-66     Citation Subset:  IM    
Affiliation:
The Celiac Center, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
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MeSH Terms
Descriptor/Qualifier:
Bone Density
Celiac Disease* / diagnosis,  physiopathology,  therapy
Diet, Gluten-Free
Female
Fertility
Glutens / metabolism
Humans
Pregnancy
Pregnancy Outcome
Prevalence
Women's Health*
Grant Support
ID/Acronym/Agency:
K23 DK082619/DK/NIDDK NIH HHS; K23 DK082619-01A1/DK/NIDDK NIH HHS; K23 DK082619-03/DK/NIDDK NIH HHS; R03 DK095937/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
8002-80-0/Glutens
Comments/Corrections

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