Document Detail


Ceftriaxone-induced toxic epidermal necrolysis mimicking burn injury: a case report.
MedLine Citation:
PMID:  20062752     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Toxic epidermal necrolysis is a rare exfoliative disorder with a high mortality rate.
CASE PRESENTATION: We present a 70-year-old woman of Iranian descent who presented with toxic epidermal necrolysis that was initially diagnosed as a scald burn. Further anamnesis prompted by spread of the lesions during hospitalization revealed that the patient had been receiving ceftriaxone for several days. To the best of our knowledge, this is the first case of ceftriaxone-induced toxic epidermal necrolysis in the English literature.
CONCLUSION: Toxic epidermal necrolysis is an acute, life-threatening, exfoliative disorder with a high mortality rate. High clinical suspicion, prompt recognition, and initiation of supportive care is mandatory. Thorough investigation of the pathogenetic mechanisms is fundamental. Optimal treatment guidelines are still unavailable.
Authors:
Sarit Cohen; Allan Billig; Dean Ad-El
Publication Detail:
Type:  Journal Article     Date:  2009-12-10
Journal Detail:
Title:  Journal of medical case reports     Volume:  3     ISSN:  1752-1947     ISO Abbreviation:  J Med Case Rep     Publication Date:  2009  
Date Detail:
Created Date:  2010-01-11     Completed Date:  2011-07-14     Revised Date:  2012-05-16    
Medline Journal Info:
Nlm Unique ID:  101293382     Medline TA:  J Med Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  9323     Citation Subset:  -    
Affiliation:
Department of Plastic Surgery, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa, Israel.
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