Document Detail


Cefotetan versus piperacillin in the prophylaxis of abdominal and vaginal hysterectomy: a prospective randomized study.
MedLine Citation:
PMID:  2686955     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective randomized study was carried out on a total of 686 patients who underwent vaginal or abdominal hysterectomy. Of these, 338 were given prophylactic cefotetan (2 g) and 348 piperacillin (2 g). Both drugs were administered as i.v. bolus 30 min before operation. Findings confirm the higher risk of infection with abdominal hysterectomy and the advantages of the long half-life cephalosporin, cefotetan.
Authors:
M Regallo; S Scalambrino; L Negri; F Landoni; C Mangioni
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Drugs under experimental and clinical research     Volume:  15     ISSN:  0378-6501     ISO Abbreviation:  Drugs Exp Clin Res     Publication Date:  1989  
Date Detail:
Created Date:  1990-01-23     Completed Date:  1990-01-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802135     Medline TA:  Drugs Exp Clin Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  IM    
Affiliation:
Obstetrics-Gynaecology Department, S. Gerardo Hospital, Monza, Italy.
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MeSH Terms
Descriptor/Qualifier:
Cefotetan / therapeutic use*
Female
Humans
Hysterectomy*
Hysterectomy, Vaginal*
Piperacillin / therapeutic use*
Premedication*
Randomized Controlled Trials as Topic
Surgical Wound Infection / microbiology,  prevention & control*
Chemical
Reg. No./Substance:
61477-96-1/Piperacillin; 69712-56-7/Cefotetan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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