| Cefaclor in the treatment of otitis media with effusion. | |
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MedLine Citation:
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PMID: 3865493 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A randomized clinical trial in which 91 children with chronic OME participated was performed. Cefaclor 20 mg/kg body weight b.i.d. was given to the treated group (n = 46) during 10 days preceding the day appointed for surgery. The control group (n = 45) remained untreated. On the day scheduled for surgery 24 (52%) of the treated cases had healed, compared to 5 (11%) of the untreated cases, a significant difference (p less than 0.001). The long term effects showed that in the treated group 18 of the 24 primarily healed remained unoperated at a median follow-up period of 20 months. In the untreated group two of the five that originally resolved later relapsed and were subjected to surgery. |
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Authors:
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S Ernstson; M Anari |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Acta oto-laryngologica. Supplementum Volume: 424 ISSN: 0365-5237 ISO Abbreviation: Acta Otolaryngol Suppl Publication Date: 1985 |
Date Detail:
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Created Date: 1986-01-22 Completed Date: 1986-01-22 Revised Date: 2008-02-13 |
Medline Journal Info:
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Nlm Unique ID: 0370355 Medline TA: Acta Otolaryngol Suppl Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 17-21 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cefaclor
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therapeutic use* Cephalexin / analogs & derivatives* Child Child, Preschool Chronic Disease Drug Evaluation Female Follow-Up Studies Humans Infant Male Otitis Media with Effusion / drug therapy* Recurrence |
| Chemical | |
Reg. No./Substance:
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15686-71-2/Cephalexin; 53994-73-3/Cefaclor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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