Document Detail


Cavitary lung nodules associated with combination chemotherapy containing bleomycin.
MedLine Citation:
PMID:  2442421     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a patient in whom multiple cavitary lung nodules developed without infectious symptoms after treatment with bleomycin, cisplatin and vinblastine combination chemotherapy for metastatic testis cancer. Open lung biopsy demonstrated extensive granuloma formation without evidence of malignancy or infection. This report extends the spectrum of bleomycin pulmonary toxicity to include cavitary pulmonary nodules associated with granuloma formation.
Authors:
J A Talcott; M B Garnick; P C Stomper; J J Godleski; J P Richie
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of urology     Volume:  138     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-10-05     Completed Date:  1987-10-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  619-20     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Bleomycin / administration & dosage,  adverse effects*
Cisplatin / administration & dosage
Dermoid Cyst / drug therapy
Granuloma / chemically induced*
Humans
Male
Middle Aged
Solitary Pulmonary Nodule / chemically induced*
Testicular Neoplasms / drug therapy
Vinblastine / administration & dosage
Grant Support
ID/Acronym/Agency:
5T32CA09172-11/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
11056-06-7/Bleomycin; 15663-27-1/Cisplatin; 865-21-4/Vinblastine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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