Document Detail


Caveats for the use of operational electronic health record data in comparative effectiveness research.
MedLine Citation:
PMID:  23774517     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The growing amount of data in operational electronic health record systems provides unprecedented opportunity for its reuse for many tasks, including comparative effectiveness research. However, there are many caveats to the use of such data. Electronic health record data from clinical settings may be inaccurate, incomplete, transformed in ways that undermine their meaning, unrecoverable for research, of unknown provenance, of insufficient granularity, and incompatible with research protocols. However, the quantity and real-world nature of these data provide impetus for their use, and we develop a list of caveats to inform would-be users of such data as well as provide an informatics roadmap that aims to insure this opportunity to augment comparative effectiveness research can be best leveraged.
Authors:
William R Hersh; Mark G Weiner; Peter J Embi; Judith R Logan; Philip R O Payne; Elmer V Bernstam; Harold P Lehmann; George Hripcsak; Timothy H Hartzog; James J Cimino; Joel H Saltz
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical care     Volume:  51     ISSN:  1537-1948     ISO Abbreviation:  Med Care     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-06-24     Completed Date:  2013-09-13     Revised Date:  2014-08-04    
Medline Journal Info:
Nlm Unique ID:  0230027     Medline TA:  Med Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S30-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Comparative Effectiveness Research / organization & administration*,  standards
Data Collection / methods*,  standards*
Data Interpretation, Statistical
Electronic Health Records / organization & administration*,  standards
Humans
Insurance Claim Review / organization & administration
Research Design / standards*
Grant Support
ID/Acronym/Agency:
1UL1RR024148/RR/NCRR NIH HHS; 2UL1RR024156/RR/NCRR NIH HHS; 5UL1RR024140/RR/NCRR NIH HHS; 5UL1RR025005/RR/NCRR NIH HHS; 5UL1RR025008/RR/NCRR NIH HHS; 8UL1TR000090/TR/NCATS NIH HHS; UL1 RR024140/RR/NCRR NIH HHS; UL1 RR024148/RR/NCRR NIH HHS; UL1 RR024156/RR/NCRR NIH HHS; UL1 RR025005/RR/NCRR NIH HHS; UL1 RR025008/RR/NCRR NIH HHS; UL1 TR000090/TR/NCATS NIH HHS
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