Document Detail

Causes of poor appetite in patients on peritoneal dialysis.
MedLine Citation:
PMID:  21195910     Owner:  NLM     Status:  In-Process    
Anorexia is common in patients with chronic kidney disease and is a main contributor to the high prevalence of protein-energy wasting in them. The peritoneal dialysis (PD) procedure may further impair appetite by causing abdominal discomfort and also through the absorption of the osmotic agent and other factors. An increased peritoneal solute transport rate has been linked to protein-energy wasting and also to the malnutrition, inflammation, and atherosclerosis syndrome, which has been associated to poor appetite and plays a role in most premature deaths in these patients. The pathogenesis of these associations is unclear. In this review, we discuss the effect of PD, in particular, PD solutions, inflammation, and increased peritoneal solute transport rate, on appetite. We also describe strategies to increase appetite in PD patients.
Sung Hee Chung; Juan Jesús Carrero; Bengt Lindholm
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation     Volume:  21     ISSN:  1532-8503     ISO Abbreviation:  J Ren Nutr     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112938     Medline TA:  J Ren Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  12-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
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