Document Detail


Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review.
MedLine Citation:
PMID:  20981293     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Until today the role of oxygen in the development of the fetus remains controversially discussed. It is still believed that lack of oxygen in utero might be responsible for some of the known congenital cardiovascular malformations. Over the last two decades detailed research has given us new insights and a better understanding of embryogenesis and fetal growth. But most importantly it has repeatedly demonstrated that oxygen only plays a minor role in the early intrauterine development. After organogenesis has taken place hypoxia becomes more important during the second and third trimester of pregnancy when fetal growth occurs. This review will briefly adress causes and mechanisms leading to intrauterine hypoxia and their impact on the fetal cardiovascular system.
Authors:
Damian Hutter; John Kingdom; Edgar Jaeggi
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Publication Detail:
Type:  Journal Article     Date:  2010-10-19
Journal Detail:
Title:  International journal of pediatrics     Volume:  2010     ISSN:  1687-9759     ISO Abbreviation:  Int J Pediatr     Publication Date:  2010  
Date Detail:
Created Date:  2010-10-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101517077     Medline TA:  Int J Pediatr     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  401323     Citation Subset:  -    
Affiliation:
Pediatric Critical Care Medicine and Pediatric Cardiology, University Children's Hospital, 3010 Berne, Switzerland.
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