| Causes of death from myocardial infarction before and after thrombolysis era: a pathologic study. | |
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MedLine Citation:
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PMID: 8942226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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One hundred and sixty-eight out of 296 patients who died of acute myocardial infarction (AMI) in the Coronary Care Unit were studied to assess the cause of death. Twenty-two of them had received thrombolytic therapy. The mean age of these patients was 64.3 +/- 18.2 years. One hundred and eight subjects were male and 60 were female. One hundred and nine cases (64.8%) showed, at postmortem examination, histopathologic alterations due to acute myocardial infarction (AMI). Death was due to heart failure in 35.8%, cardiogenic shock in 20% and ventricular arrhythmia in 44%. The other 59 patients died from complications superimposed upon AMI: reinfarction (23.7%), heart rupture (40.7%), myocardial fibrosis and reinfarction (18.6%), and cerebral infarction (17%). Two of these patients also showed massive pneumonia. In those subjects who had received thrombolytic therapy, a broad spectrum of arrhythmic and haemorrhagic complications were seen (68%). Four causes of death were seen in the subjects studied: AMI, superimposed cardiac complications, side-effects of thrombolytic treatment, and non-cardiac causes. Patients who did not receive thrombolysis mechanical events eg heart failure, characterized their deaths. In subjects who had received thrombolytic therapy, arrhythmic and haemorrhagic were widely observed. |
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Authors:
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A Leone |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Singapore medical journal Volume: 37 ISSN: 0037-5675 ISO Abbreviation: Singapore Med J Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1997-01-07 Completed Date: 1997-01-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404516 Medline TA: Singapore Med J Country: SINGAPORE |
Other Details:
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Languages: eng Pagination: 270-2 Citation Subset: IM |
Affiliation:
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City Hospital, Division di Medicine, Ospedale di Pontremoli, Pontremoli (MS), Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Aged Aged, 80 and over Autopsy Female Hospital Mortality* Humans Male Middle Aged Myocardial Infarction* / drug therapy, mortality, pathology Sex Distribution Singapore Survival Rate Thrombolytic Therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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