Document Detail


Causes of chronic orthostatic hypotension.
MedLine Citation:
PMID:  8031210     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the frequency of various causes of orthostatic hypotension. DESIGN: Survey. SETTING: Tertiary referral center. PATIENTS: One hundred patients with moderate to severe orthostatic hypotension. RESULTS: Twenty-seven percent of the patients had primary autonomic failure, 35% had secondary autonomic failure, and 38% had hypotension without evidence of generalized autonomic degeneration. CONCLUSIONS: In a tertiary referral center, only a minority of patients with severe orthostatic hypotension will have Shy-Drager syndrome or Bradbury-Eggleston syndrome as their primary disease. Occasional patients who initially appear to have Bradbury-Eggleston syndrome ultimately prove to have Shy-Drager syndrome or paraneoplastic autonomic failure. Antidepressant drugs, even in low doses, remain a major overlooked cause of orthostatic hypotension.
Authors:
D Robertson; R M Robertson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of internal medicine     Volume:  154     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-08-10     Completed Date:  1994-08-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1620-4     Citation Subset:  AIM; IM; S    
Affiliation:
Department of Medicine, Vanderbilt University, Nashiville, Tenn.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Chronic Disease
Female
Humans
Hypotension, Orthostatic / etiology*
Male
Middle Aged
Grant Support
ID/Acronym/Agency:
HL14192/HL/NHLBI NIH HHS; HL44589/HL/NHLBI NIH HHS; RR00095/RR/NCRR NIH HHS
Investigator
Investigator/Affiliation:
D Robertson / Vanderbilt U, Nashville, TN

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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