Document Detail


Caught in translation: innate restriction of HIV mRNA translation by a schlafen family protein.
MedLine Citation:
PMID:  23128674     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Human immunodeficiency virus type 1 (HIV-1) is the cause of AIDS. In recent years it has emerged that cellular interferon-stimulated genes (ISG), play important roles in cell-intrinsic restriction of HIV replication. A publication now describes a novel strategy employed by HIV-infected cells to restrict viral replication, which involves inhibition of viral mRNA translation by the ISG Schlafen 11.
Authors:
Martin R Jakobsen; Trine H Mogensen; Søren R Paludan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-06
Journal Detail:
Title:  Cell research     Volume:  -     ISSN:  1748-7838     ISO Abbreviation:  Cell Res.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9425763     Medline TA:  Cell Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1] Department of Biomedicine, University of Aarhus, Aarhus, Denmark [2] Aarhus Research Center for Innate Immunology, Aarhus University, Aarhus, Denmark.
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