Document Detail


Caudal anaesthesia with 0.375% ropivacaine or 0.375% bupivacaine in paediatric patients.
MedLine Citation:
PMID:  9640159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have determined the effectiveness and degree of motor block produced by the new local anaesthetic, ropivacaine, when used for caudal anaesthesia in children. We studied 60 children, aged 3-6 yr, ASA I, allocated randomly in a double-blind manner, to receive one of two local anaesthetics: 0.375% ropivacaine 1.0 ml kg-1 or 0.375% bupivacaine 1.0 ml kg-1. Patients were anaesthetized with continuous infusion of propofol 200 micrograms kg-1 min-1. The lungs were ventilated with 50% nitrous oxide in oxygen. Heart rate and arterial pressure were measured every 5 min after administration of local anaesthetic until discharge from the recovery room. The extent of motor block in the recovery room was scored as 1-3. Adverse events and time to first analgesic requirements were recorded. Patients in the two groups did not differ in age, weight or height. There were no differences in heart rate or arterial pressure between the two groups. No adverse events were observed. The degree of motor block was significantly different between the two groups. The ropivacaine group showed a shorter duration of motor block than the bupivacaine group (P < 0.05). Postoperative analgesia was required at a mean time of 5 (SD 3.2) h in the ropivacaine group compared with 5 (2.8) h in the bupivacaine group. These findings suggest that caudal anaesthesia with ropivacaine in paediatric patients is effective and produces less motor block in the postoperative period.
Authors:
M J Da Conceicao; L Coelho
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  80     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-07-06     Completed Date:  1998-07-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  507-8     Citation Subset:  IM    
Affiliation:
Department of Anaesthesiology, Santa Catarina Federal University, Florianopolis, SC, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Amides* / pharmacology
Anesthesia, Caudal / methods*
Anesthetics, Local* / pharmacology
Bupivacaine* / pharmacology
Child
Child, Preschool
Cryptorchidism / surgery
Double-Blind Method
Hemodynamics / drug effects
Humans
Male
Movement / drug effects
Postoperative Period
Chemical
Reg. No./Substance:
0/Amides; 0/Anesthetics, Local; 2180-92-9/Bupivacaine; 84057-95-4/ropivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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