| Cauda equina syndrome in ankylosing spondylitis (the CES-AS syndrome): meta-analysis of outcomes after medical and surgical treatments. | |
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MedLine Citation:
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PMID: 11586143 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The cauda equina syndrome in ankylosing spondylitis (the CES-AS syndrome) is marked by slow, insidious progression and a high incidence of dural ectasia in the lumbosacral spine. A high index of suspicion for this problem must be maintained when evaluating the patient with ankylosing spondylitis with a history of incontinence and neurologic deficit on examination. There has been disagreement in the literature as to whether surgical treatment is warranted for this condition. A meta-analysis was thus performed comparing outcomes with treatment regimens. Our results suggest that leaving these patients untreated or treating with steroids alone is inappropriate. Nonsteroidal antiinflammatory drugs may improve back pain but do not improve neurologic deficit. Surgical treatment of the dural ectasia, either by lumboperitoneal shunting or laminectomy, may improve neurologic dysfunction or halt the progression of neurologic deficit. |
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Authors:
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N U Ahn; U M Ahn; L Nallamshetty; B D Springer; J M Buchowski; L Funches; E S Garrett; J P Kostuik; K M Kebaish; P D Sponseller |
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Publication Detail:
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Type: Case Reports; Journal Article; Meta-Analysis |
Journal Detail:
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Title: Journal of spinal disorders Volume: 14 ISSN: 0895-0385 ISO Abbreviation: J Spinal Disord Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-10-04 Completed Date: 2001-12-04 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8904842 Medline TA: J Spinal Disord Country: United States |
Other Details:
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Languages: eng Pagination: 427-33 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, Maryland, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Inflammatory Agents, Non-Steroidal / therapeutic use Humans Logistic Models Lumbosacral Region / surgery Male Odds Ratio Polyradiculopathy / drug therapy, surgery* Spinal Cord Injuries / diagnosis, surgery Spondylitis, Ankylosing / drug therapy, surgery* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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