| Catheter obstruction effect on pulsatile flow rate--pressure drop during coronary angioplasty. | |
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MedLine Citation:
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PMID: 10396693 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The coupling of computational hemodynamics to measured translesional mean pressure gradients with an angioplasty catheter in human coronary stenoses was evaluated. A narrowed flow cross section with the catheter present effectively introduced a tighter stenosis than the enlarged residual stenoses after balloon angioplasty; thus elevating the pressure gradient and reducing blood flow during the measurements. For resting conditions with the catheter present, flow was believed to be about 40 percent of normal basal flow in the absence of the catheter, and for hyperemia, about 20 percent of elevated flow in the patient group. The computations indicated that the velocity field was viscous dominated and quasi-steady with negligible phase lag in the delta p(t)-u(t) relation during the cardiac cycle at the lower hydraulic Reynolds numbers and frequency parameter. Hemodynamic interactions with smaller catheter-based pressure sensors evolving in clinical use require subsequent study since artifactually elevated translesional pressure gradients can occur during measurements with current angioplasty catheters. |
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Authors:
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R K Banerjee; L H Back; M R Back; Y I Cho |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of biomechanical engineering Volume: 121 ISSN: 0148-0731 ISO Abbreviation: J Biomech Eng Publication Date: 1999 Jun |
Date Detail:
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Created Date: 1999-09-28 Completed Date: 1999-09-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7909584 Medline TA: J Biomech Eng Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 281-9 Citation Subset: IM |
Affiliation:
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Fluent, Inc., Lebanon, NH 03766, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Angioplasty, Transluminal, Percutaneous Coronary / adverse effects* Blood Flow Velocity* Blood Pressure / physiology* Humans Models, Cardiovascular Pulsatile Flow / physiology* Stress, Mechanical Time Factors |
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