Document Detail

Catheter-associated fungemia due to Exophiala oligosperma in a leukemic child and review of fungemia cases caused by Exophiala species.
MedLine Citation:
PMID:  17033790     Owner:  NLM     Status:  MEDLINE    
A case of catheter-associated fungemia due to Exophiala oligosperma in a 3-year-old leukemic child is presented. The etiologic agent was isolated from blood specimens and the catheter tip. The isolate was identified by its morphological characteristics and DNA sequencing of the internal transcribed spacer region of rDNA. Despite initial amphotericin B and itraconazole therapy, the child's fever subsided only after removal of the catheter. A review of the medical literature revealed 29 cases of infection due to Exophiala species. Twenty-three of these 29 patients had a CVC in place when they developed fever or other manifestations of fungemia. Withdrawal of the CVC together with amphotericin B and/or itraconazole therapy generally resulted in a good prognosis.
I Al-Obaid; S Ahmad; Z U Khan; B Dinesh; H M Hejab
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology     Volume:  25     ISSN:  0934-9723     ISO Abbreviation:  Eur. J. Clin. Microbiol. Infect. Dis.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-11-22     Completed Date:  2007-01-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8804297     Medline TA:  Eur J Clin Microbiol Infect Dis     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  729-32     Citation Subset:  IM    
Department of Microbiology, Al-Sabah Hospital, Shuwaikh, Kuwait.
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MeSH Terms
Catheterization, Central Venous / adverse effects*
Child, Preschool
Exophiala / classification,  genetics,  isolation & purification*
Fungemia / microbiology*
Mycoses / microbiology*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*

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