Document Detail


Catheter ablation using radiofrequency energy.
MedLine Citation:
PMID:  2407395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recently, transvenous catheter ablation using radiofrequency impulses has been applied in experimental animals as well as in humans. This review describes the biophysics, mechanisms, and tissue effects of radiofrequency alternating current. Ablation of the AV-junction has been performed in experimental studies as well as in a growing number of patients. Complete AV-block or modification of the AV conduction by RF-current application can be achieved in about 45-65% of patients. Presently about 50% of patients with rightsided accessory pathways can be successfully managed using radiofrequency impulses. Certain limitations exist using a biopolar "epi-endocardial" electrode configuration for leftsided accessory pathways. Only few studies are available concerning the use of RF ablation of ventricular tachycardia foci. As most experimental investigations were carried out in structurally nondiseased myocardium, the use of this new technique in fibrotic or scarred tissue warrants further studies. Radiofrequency catheter ablation seems to be feasible and relatively safe for the treatment of otherwise drug-refractory supraventricular arrhythmias; further studies are needed to assess the safety and efficacy in patients with drug-refractory ventricular tachyarrhythmias.
Authors:
M Borggrefe; G Hindricks; W Haverkamp; G Breithardt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  13     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-04-10     Completed Date:  1990-04-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  127-31     Citation Subset:  IM    
Affiliation:
Department of Cardiology-Angiology, Medical Hospital, Westfälische Wilhelms Universität Münster, Federal Republic of Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arrhythmias, Cardiac / surgery*
Electrocoagulation / instrumentation*
Heart Catheterization / instrumentation*
Heart Conduction System / surgery*
Humans
Tachycardia / surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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