Document Detail

Catheter ablation for atrial fibrillation in patients with the Marfan and Marfan-like syndromes.
MedLine Citation:
PMID:  17952580     Owner:  NLM     Status:  MEDLINE    
Patients with the Marfan syndrome may pose a difficult challenge for catheter-based interventions due to frequent coexisting valve disease, potential delay in vascular healing and repair, and intra-atrial scar from prior cardiac surgery. We report a case series of four patients with Marfan or Marfan-like syndromes who underwent ablation for drug-refractory atrial fibrillation. Ultimately three of four patients remained in sinus rhythm, however most patients required multiple ablative attempts and long-term atrial flutter was common. Nonetheless, peri-procedural complications were minimal despite the connective tissue disorder and prosthetic valves in three of four patients. In conclusion, catheter ablation of AF in patients with Marfan syndrome is a viable option in those individuals refractory to conventional therapy.
T Jared Bunch; Heidi M Connolly; Samuel J Asirvatham; Peter A Brady; Bernard J Gersh; Thomas M Munger; Win-Kuang Shen; Kristi H Monahan; Douglas L Packer
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-10-20
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  20     ISSN:  1383-875X     ISO Abbreviation:  J Interv Card Electrophysiol     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-13     Completed Date:  2008-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  15-20     Citation Subset:  IM    
Department of Internal Medicine, Mayo Clinic, Rochester, MN 55902, USA.
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MeSH Terms
Atrial Fibrillation / diagnosis*,  surgery*
Catheter Ablation / methods*
Marfan Syndrome / diagnosis*,  surgery*
Middle Aged
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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