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Catheter-Directed Thrombolysis for Acute Iliofemoral Deep Venous Thrombosis.
MedLine Citation:
PMID:  21306867     Owner:  NLM     Status:  Publisher    
Patients with acute iliofemoral deep venous thrombosis often experience severe postthrombotic complications that result from venous obstruction and valve incompetence. Conventional anticoagulation prevents thrombus extension, fatal pulmonary embolism, and recurrence of the deep venous thrombosis, but it can hardly minimize the postthrombotic complications. Whether early thrombus removal significantly reduces the postthrombotic morbidity is an important question related to the treatment of these patients. This article will chiefly introduce rationale for and evidence supporting early thrombus removal for acute iliofemoral deep venous thrombosis, and the development and current status of catheter-directed thrombolysis and adjunctive percutaneous mechanical thrombectomy or pharmacomechanical thrombolysis, which are usually the first line of therapy for early removal of an acute thrombus in the proximal veins of the leg. In addition, we will briefly introduce the development of new pharmacologic agents.
Fang Liu; Ping Lü; Bi Jin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-8
Journal Detail:
Title:  Annals of vascular surgery     Volume:  -     ISSN:  1615-5947     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Annals of Vascular Surgery Inc. Published by Elsevier Inc. All rights reserved.
Department of Radiology, Union Hospital, Huazhong University of Science and Technology, Hubei Province, People's Republic of China.
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