Document Detail

Catheter-based therapies for massive pulmonary embolism.
MedLine Citation:
PMID:  20226960     Owner:  NLM     Status:  MEDLINE    
Massive pulmonary embolism carries a high mortality rate as a result of right ventricular failure. In addition to anticoagulation, systemic thrombolysis is the standard first line of therapy for patients with life-threatening massive pulmonary embolism. Surgical embolectomy is often considered in patients with contraindications to receiving systemic thrombolysis or when thrombolysis has failed. Surgical embolectomy is not without inherent risk and limitations.Although there is a paucity of large clinical trials, available data suggests catheter-based treatment of massive pulmonary embolism restores hemodynamic stability and thus is an alternative to surgical therapy.
Thomas M Todoran; Piotr Sobieszczyk
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  52     ISSN:  1873-1740     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-04-01     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  429-37     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Cardiovascular Division, Vascular Medicine Section, Brigham and Women's Hospital, Boston, MA 02115, USA.
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MeSH Terms
Anticoagulants / therapeutic use
Catheterization / adverse effects,  instrumentation,  methods*
Combined Modality Therapy
Equipment Design
Fibrinolytic Agents / administration & dosage*
Pulmonary Embolism / physiopathology,  radiography,  therapy*
Risk Assessment
Thrombectomy* / adverse effects,  instrumentation
Thrombolytic Therapy* / adverse effects,  instrumentation
Treatment Outcome
Reg. No./Substance:
0/Anticoagulants; 0/Fibrinolytic Agents

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